Corneal Crosslinking Biomechanics Evaluated By a Novel and Easily Implemented Differential Tonometry Method | ASCRS
Presentation
Corneal Crosslinking Biomechanics Evaluated By a Novel and Easily Implemented Differential Tonometry Method
May 2020
Meeting: 2020 Virtual Annual Meeting
Session: SPS-106 Keratoconus: Measurements, Treatments, New Technology
Authors: Sean J. McCafferty, MD, FACS, Nathan Radcliffe MD
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Purpose
Evaluate corneal rigidity changes following corneal crosslinking (CCL) by paired differential tonometry IOP measurements with a Goldmann tonometer (GAT) using both a standard GAT prism and corneal compensating GAT prism.

Methods
IOP was measured on 18 unique eyes undergoing CCL for keratoconus with a GAT using a standard flat prism and a curved corneal error correcting prism before treatment and 2 weeks, 2 months and 6 months after treatment. Concurrent measurements of Central corneal thickness CCT and corneal hysteresis CH were completed.

Results
Paired IOP measurements with standard and corneal correcting GAT prisms indicated a significant sustained relative increase in the differential IOP between the two prisms after CCL (p=0.005,0.015). CH initially decreased at two weeks post-CCL then returned to sustained pre-op levels (p=0.033,0.20). CCT progressively decreased following CCL (p=0.002).

Conclusion
Differential tonometry between standard and corneal biomechanical compensating GAT prisms demonstrated it as a simple and sensitive measurement of changes in corneal rigidity and corneal stress redistribution.
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This presentation is from the session "SPS-106 Keratoconus: Measurements, Treatments, New Technology" from the 2020 ASCRS Virtual Annual Meeting held on May 16-17, 2020.

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